NSG6005 Advanced Pharmacology FL02 Week 6.docx - Week 6 Discussion 1 There aren't any reliable differentiating signs or symptoms functional heartburn

NSG6005 Advanced Pharmacology FL02 Week 6.docx - Week 6...

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Week 6 Discussion 1 There aren't any reliable differentiating signs or symptoms; functional heartburn denotes endoscopy-negative heartburn. A normal esophageal pH study differentiates between nonerosive GERD and functional heartburn. An alternative is a normal impedance-pH study. These studies would usually be done in patients who fail to respond to proton-pump inhibitor (PPI) therapy. Referral to a gastroenterologist to diagnose and treat GERD is necessary as well (Woo, & 2015). A short trial 8 weeks of PPIs and lifestyle therapy such as weight loss if needed, and elevation of the head off the bed for nocturnal features should be initiated. Medications include a standard-dose proton-pump inhibitor, omeprazole: 20 mg orally once daily, omeprazole/sodium bicarbonate: 20/1100 mg to 40/1100 mg (capsule) orally once daily; or 20/1680 mg to 40/1680 mg (powder) orally once daily. Esomeprazole: 20-40 mg orally once daily, rabeprazole: 20 mg orally once daily, pantoprazole: 40 mg orally once daily, lansoprazole: 15-30 mg orally once daily
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  • Fall '16
  • Gastroesophageal reflux disease, proton-pump inhibitor

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