Respiratory - Chapter 54 Drugs Acting on the Upper Respiratory Tract Copyright 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Drugs Used to

Respiratory - Chapter 54 Drugs Acting on the Upper...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 54: Drugs Acting on the Upper Respiratory Tract Chapter 54: Drugs Acting on the Upper Respiratory Tract
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Drugs Used to Treat Upper Respiratory Infections Drugs Used to Treat Upper Respiratory Infections Antitussives Block the cough reflex Decongestants Decrease the blood flow to the upper respiratory tract and decrease the overproduction of secretions Antihistamines Block the release or action of histamine that increases secretions and narrows airways
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Drugs Used to Treat Upper Respiratory Infections (cont.) Drugs Used to Treat Upper Respiratory Infections (cont.) Expectorants Increase productive cough to clear airways Mucolytics Increase or liquefy respiratory secretions to aid clearing of airways
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Use of Upper Respiratory Tract Agents Across the Lifespan Use of Upper Respiratory Tract Agents Across the Lifespan
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antitussives Antitussives Suppress the cough reflex Codeine (generic only) Hydrocodone (available in some combination products) Dextromethorphan (generic and in combination products)
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antitussives Antitussives Actions Act directly on the medullary cough center of the brain to depress the cough reflex Indications Control nonproductive cough Pharmacokinetics Rapidly absorbed, metabolized in the liver, and excreted in the urine
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Antitussives (cont.) Antitussives (cont.) Contraindications Patients who need to cough to maintain the airway Head injury or impaired CNS Caution Hypersensitivity or history of narcotic addiction Adverse Effects Drying effect on the mucous membranes CNS adverse effects and GI upset Drug-to-drug interactions- MAOI’s
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Nursing Considerations for Antitussives Nursing Considerations for Antitussives Assess: History and Physical Exam and history of allergy Temperature, respirations, adventitious sounds Orientation and affect
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Prototype Antitussives Prototype Antitussives
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Oral Decongestants Oral Decongestants Decrease nasal congestion related to the common cold, sinusitis, and allergic rhinitis - Pseudoephedrine ( Triaminic Allergy Congestion , and many combination products)
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Oral Decongestants Oral Decongestants Actions Shrink the nasal mucous membrane by stimulating the alpha-adrenergic receptors in the nasal mucous membranes Indications Promotion of drainage in the sinuses and improving air flow
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