2212 Lecture 10 Study Guide.doc

2212 Lecture 10 Study Guide.doc - Lecture 10 Study Guide 1...

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Lecture 10 - Study Guide 1) A. What is “energy coupling” and what molecule does this process primarily involve? (Pg. 150, Bold Face ) a. The way cells manage their energy. Use of an exergonic process to drive an endergonic one. B. How does phosphorylation from an ATP molecule couple an endergonic and exergonic reaction? (Pg. 151, final paragraph) b. The cell is able to use the energy released by ATP hydrolysis directly to drive chemical reactions that, by themselves, are endergonic. If the delta G of an endergonic reaction is less than the amount of energy released by ATP hydrolysis, then the two reactions are coupled to be exergonic. 2) How does ATP release more energy than most other organic molecules? (Pg. 151, column 2, paragraphs 2-3) - All three-phosphate groups are negatively charged. These like charges are crowded together and their mutual repulsion contributes to the instability of this region of the ATP molecule. The triphosphate tail of ATP is the chemical equivalent of a compressed spring. 3) A. What is free energy of activation (E A )? B. How does free energy of activation relate to the transition state ? (Pg. 154, paragraph 1 and Figure 8.13)
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