13.1 Respiratory Case Study- group pharm.docx - 1 How will...

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1 . How will you respond to Mr. Sebelius’ statement ? The symptoms presented by Mr. Sebelius are non-productive cough, temperature of 102.4, scratchy throat, and chills exhibiting signs of a viral infection. Antibiotics treat bacterial infections which would not be effective for treatment causing antibiotic resistance or harmful side effects [CDC155]. When there is antibiotic resistance good bacteria are killed leading to complications like diarrhea. When the organism is resistant it becomes harder to kill causing a stronger antibiotic used for the next illness. 2. What antiviral agents are prescribed for influenza A? Increased resistant strains of viruses’ leaves two known medications no longer useful for treatment of influenza A which are Amantadine (Symmetrel) and rimantadine (Flumadine). The Federal Drug Administration (FDA) prevents the use of them because resistance has been seen in high levels among patients [Woo16]. The now approved treatment includes zanamivir (Relenza), oseltamivir (Tamiflu), and peramivir (Rapivab). These drugs should only be administered less than fourty eight hours from onset of symptoms. 3. What are the dosage ranges, action, use, pharmacokinetics, pharmacodynamics, drug-to- drug interactions, drug to herbal or food interactions, contraindications, adverse effects, guidelines for administration, and patient teaching for the administration of antiviral agents ? The mechanism of action relating to zanamivir, oseltamivir, and peramivir are neuramindase inhibitors which are a viral enzymes that cleave viruses attaching to a host permitting viral circulation making them active against influenza A and B [Woo16]. Dosages range with all three medications and adherence is imperative for treatment.

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