Harnessing the Central DogmaYou are familiar with the central dogma, however, I wanted to give you some practice with what it's rules imply. To do this we will work though the first dozen questions and you will do the last ones on your own. When you are finished, please hand it the worksheet for credit.1. Describe the differences between the structure of DNA vs. RNA.2'-OHU in RNA, T in DNADNA is less rigidDNA minor and major grooves. RNA both grooves more open2. Why is DNA used for hereditary information and not RNA?3. When two DNA strands hybridize together, they interaction is mostly stabilized by4. The ribosome is made of5. How does DNA polymerase determine which base is next in a growing DNA chain?It randomly grabs nucleotides and tries them!6. What is this picture showing?7.. What direction is transcriptionhappening?A. TranscriptionB. TranslationC. BothD. Neither
8. What direction is translation happening?9. In both eukaryotes and prokaryotes RNA polymerase recognizes the transcriptional start site by10. If you delete a promoter to a gene, it wouldA. Function almost normally
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- Spring '09