B+Btest3

B+Btest3 - Learning : how experience changes the brain...

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Learning : how experience changes the brain Memory : how these changes are stored and subsequently reactivated Classical Conditioning Operant Conditionaing Lashley’s search for the engram EXAMPLE: H.M.- Bilateral medial temporal lobectomy Hippocampus, amygdala, adjacent cortex Generalized convulsions eliminated, reduced occurrence of seizures Normal perceptual, motor, intellectual abilities Mild retrograde amnesia Anterograde amnesia, global amnesia Many tests used to access HM Types of Memory -Declaritive - Semantic - Episodic -Procedural R.B.- Another patient with medial temporal lobe amnesia. Caused by cerebral ischemia. Post-mortem observation of damage to CA1 pyramidal cells of hippocampus. Korsakoff’s Syndrome - Associated w/ alcoholism (& prolonged thiamine deficiency). Sensory and motor deficits, extreme confusion, personality changes. Initially, anterograde amnesia for explicit episodic memories. As disease progresses, severe retrograde amnesia. Damage to medial diencephalon and diffuse damage to hippocampus, cerebellum, parts of cortex. Alzheimer’s Disease
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This note was uploaded on 03/27/2008 for the course NS 376 taught by Professor Wee during the Spring '08 term at Tulane.

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B+Btest3 - Learning : how experience changes the brain...

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