Cirrhosis of the Live_stu_2015.pdf - DEFINITION Cirrhosis...

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10/23/2015 1 CIRRHOSIS OF THE LIVER NURN 236 DEFINITION Cirrhosis is a chronic, progressive disease of the liver resulting in excessive degeneration and distortion of liver cells. TYPES OF CIRRHOSIS 1. Alcoholic -the scar tissue characteristically surrounds the portal areas. Frequently caused by chronic alcoholism and is the most common type of cirrhosis. 2. Postnecrotic- there are broad bands of scar tissue. Late result of a previous bout of acute viral hepatitis. 3. Biliary- scarring occurs in the liver around the bile ducts. Usually results from chronic biliary obstruction and infection called cholangitis, less common. PATHOPHYSIOLOGY Cirrhosis a result of necrosis of liver cells liver cells are gradually replaced by scar tissue disease usually has an insidious onset and a protracted course, occasionally proceeding over a period of 30 or more years 4 CATEGORIZING CIRRHOSIS AND CLINICAL MANIFESTATIONS. Compensated cirrhosis with its less severe often vague symptoms may be discovered secondarily at a routine physical examination. Decompensated cirrhosis result from failure of the liver to synthesize proteins, clotting factors, and other substances manifestations of portal hypertension
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