Exam #1 - BBMB 405 EXAM 1 February 9, 2007 Name 1. (2 pts)...

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Unformatted text preview: BBMB 405 EXAM 1 February 9, 2007 Name 1. (2 pts) What comes in and what comes out from the Calvin cycle? 2. (6 pts) Rubisco catalyzes the following reaction: (IZH20PO32' CHZOP032' T=o coz Ho—clz—coo- H20 ' TH10P032' H—T—OH A» c=o 2 HO—(li—H H—C—OH H—C—OH co,- CH20P032" CH20P032' Ribuloso Unstable 3-Phosphoglyteruie l,5-bispl|osphalo inhrmediulo Ummbmedfisunpgm lbdllmlury. six-I. mum 4: 2007 w. urn-cam ma Comp-n, What other reactive molecule can Rubisco bind in the active site instead of C02? What products are formed in that case? What do plants do to save/recycle carbons from these products? (In other words: what is the fate of the wasteful reaction products?) 3. (2 pts) At high temperatures, Rubisco has low affinity for CO; What adaptation do C4 plants have to make Rubisco more efficient? 4. (2 pts) Light absorbed by a chlorophyll a causes a. an electron to move from the photon to the chlorophyll. .mn ron o m v - om ; mm s a e 0 an excited state. c. an electron to move to a neighboring water mo ecu c d. an electron to move from chlorophyll to ADP. e. none of the above. Circle the correct answer. 5. (2 pts) What is the original source of electrons used to neutralize the special pair in photosystem II? a. reduced cytochrome bf b. NADH !. memlrane lipids e. ferredoxin Circle the correct answer. 6. (4 pts) Describe the process of cyclic photophosphorylation in your favorite green house plant (e.g., what C0I1I§0§§nts participate and what is produced). "V. \ ‘ 1%., 4N5 F; ’6" 7-10 3%? A? \3 L’tLL > W £2006 Fe. 4) 71m 7. (5 pts) A person whose muscle is deficient in glycogen phosphorylase is less responsive to the fright-stimulated release of epinephrine (adrenalin) to blood. Justify your answer. A.— 54? True or False T => ‘ 8. (4 pts) Several physiological modes of the pentose phosphate pathway are possible for meeting the metabolic need for NADPH, ribose 5-phosphate, and ATP. In one scenario, such as found in adipose tissue, much more NADPH is required than ribose-S-phosphate. How is this need maintained. ygpffi “MP/pl 47%(Mé—(Zafiu mm @FW « Na ~$_p “’26 724.2%“ 574% ,- 9. (4 pts) If there are defects of G—6—P dehydroenase and 6-phosphogluconate dehydrogenase in sympathetic neurons, would you expec high, or normal (circle correct answer) amount of norepinephrine in synaptic vesicles. Justify your answer. W /\ (19”me ) at J v -, \ M/a‘DPI W019 Sf“ A/fil—flP/p: % ‘0” 10. (8 pts) Several organs of a lactating female such as a dairy cow pa cipate in the causation, symptoms, and recovery of/from lactation ketosis. Name the principal organ involved in the following events. a) Release of long—chain fatty acids into blood W ’Wfl‘i—fi . M g 5 322?, b) Oxidation of B~hydroxybutyrate to CO2 ’mW) c) Synthesis of acetoacetate d) Source of greater flux of amino acids into blood , e) Anatomical site of amino acid conversion to blood glucose f) Organ responsible for elimination of unoxidized ketone [S % bodies from the body g) Organ responsible for secretion of insulin and glucagon PM 44$ into blood h) Organ responsible for conversion of oleic acid to acetoacetate i; Q E: 11. These questions pertain to regulation of glycogen metabolism. For each stimulus, state whether rates of glycogen synthesis and degradation are increased or decreased (Effect) and then explain why the rate change occurs (Why). 1/ (4 pts) a. Neural stimulation of skeletal muscle for a vigorous contraction Effect? . , z ' ‘ 2 I ' J wok Afllbzz’“ ‘ (4 pts.) b. Consumption of “caffeinated” coffee at Starbucks at your local HyVee Store on glycogen metabolism in liver Effect?tL i i 2 a aw“; 414% c 04/ij gig; if” 7o/fMFT—57‘PM—élf’ .a 47 6‘“ 12. (5 pts) Indicate how the pentose phosphate pathway participates in maintaining a low concentration of superoxide ions (02‘) in erythrocytes (RBCs) 0.. M’” H gas/2‘2 9‘ l \ 5 2/0 92H»? OD L 7 X; 6,51; GssG Man/Z W’HH‘” l3. (4 pts) Why are fatty acids with odd number of carbons advisable for you to consume if your diet contains no carbohydrate? W 6255;] “MM. 03- N/fi x1; 14. (ZSEpts) zgutline the reactiéns tlfit a tr‘olein (glycerol + 3 oleates) molecule in today’s lunch must undergo to be stored as a trioleihdgyour adipose tissue. Indicate the organs where reactions occur. ) 0) 3 d7 15. (3 pts) A particular type of seal that lives in Newfoundland gives birth to its young and then nurses the baby for a period of time when totally fasting. Is hormone—sensitive lipase (HSL) and albumin necessary for the “transfer” of triacylglycerol from the seal’s adipose tissue to triacylglycerol in milk? %& . Explain. Yes or 0. TAG—[iiiéBWuLZQ/éw/ TH: géa W>m W74] #4 #32 ,we/ 16. (4 pts) Does skeletal muscle release glucose from its glycogen stores to the blood for transport to your brain? %— . Justify your answer. Yes or N o wager. {WLLMWW W ;Q*/—FL M 91/0 G“é"‘ 4w Mata WY: (pk/0% l7. (4 pts) Why is the NADH to NAD+ ratio unusually high in liver of ketotic human baby? 18. (5 pts) What is the difference in moles of ATP yield for the oxidation of one mole of the following compounds to C02? Stearic (C—1820) and oleic acids (C—l8:l) Z . 5 ( #24) fi-Hydroxybutyrate and acetoacetate 2 5 ( WNW-'3” ) Palmitate and palmitoyl-CoA a @‘Tfl‘a ISL/“’2 79 Acetate and acetyl—COA i (’é'rd —-‘> W”? Butyrate (04:0) and hexanoate (C-620) / f ( 42.474 “van/v :L F/o‘oh’ (lb) 4.5“ luf— 19. (6 pts) For each of the following unsaturated fatty acids, indicate whether the biosynthetic precursor in animals is palmitoleate (16:1), oleate (18:1), linoleatc (18:2), or linolenate (18:3). Showsome work. a. 18:1 cis—All ~ —-« C ; A '/ 0‘! -1 : C— J c 4. I m 9 IS / ,n. b. 18:3 cis—A“, A”, M“ c- ["31 A 9 I2. 4 4’ z [a C' / 33?— ’ m5 “[233 c 22:6 cis-A“, A7, A‘", A”, A”, A” ~ Afi/é/S- Aég/zb" A31! ['7’ )7 v J j ’ J (Le/(3‘3 >C~xzw W’ :96-20, 54 Cc c5? 20. (6 pts) Is citrate cleavage enzyme (ATchitrate lyase) necessary for synthesis of stearate (C— 18:0) from glycerol in your liver. R ggg Explain. Y s or No 21. (5 pts) Name the major compound (or compounds) that is (are) absorbed from blood for the following metabolic processes: a. Milkfat synthesis in the human mammary gland using the esterified fatty acids stored in adi ose tissu (ignoret e gly e/rol ie ). _ Ali )Efi/G- F161) F55" b. De noEoZ sinthesis of palmltate by liver of White Leghorn hens (nonruminant). c. Synthesis of prostaglandin E2 in the bovine ovary. (3‘2 2.5! d. Synthesis of ribose-S—phosphate for DNA replication in a cancer of the human lung. M e. The oxygen in water produced during conversion of palmitate to 16 C02. PDH) 22. Is pyruvatc deS’iydrogcnasc activity necessary for a respiring rat liver slice to convert propionate to: a. (3 pts) Glucose? 71/0 Explain Yes or No f%%fi;%a&r—>~SSL¢94%4~>Aflfifig—~9fi57*4>*9(ézuwmao b. (3 pts) C02? 4% Explain ...
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This note was uploaded on 03/27/2008 for the course BBMB 405 taught by Professor Beitz during the Spring '08 term at Iowa State.

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Exam #1 - BBMB 405 EXAM 1 February 9, 2007 Name 1. (2 pts)...

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