Cell Communication

Cell Communication - CELL COMMUNICATION ALL organisms need...

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CELL  COMMUNICATION v   ALL organisms need to  monitor their environment v   All multicellular organisms  need cell-cell communication Ø   Cellular receptors evolved Ø   Signal transduction pathways Ø   Cellular effectors for response  11_05CellSignaling_A.swf
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Three Stages of Cell Communication (Ligand) (High ligand affinity) evoked by ligand-receptor binding highly conserved (very few different pathways) specificity via cell-specific protein expression
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Communication by Direct Contact Direct passage of ligand between cells through junction Direct contact of extracellular molecules
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Communication via Secreted Ligand (b) Synaptic signaling. A nerve cell releases neurotransmitter molecules into a synapse, stimulating the target cell. Local regulator diffuses through extracellular fluid Target cell Secretory vesicle Electrical signal along nerve cell triggers release of neurotransmitter Neurotransmitter diffuses across synapse Target cell is stimulated LOCAL SIGNALING An example of paracrine signaling Autocrine signaling : self stimulation Paracrine signaling: neighbor cell stimulation
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Hormone travels in bloodstream to target cells (c) Hormonal signaling. Specialized endocrine cells secrete hormones
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This note was uploaded on 03/28/2008 for the course BIOL 212 taught by Professor Shen during the Spring '08 term at Iowa State.

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Cell Communication - CELL COMMUNICATION ALL organisms need...

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