Translation - TRANSLATION RNA-directed polypeptide...

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TRANSLATION RNA-directed polypeptide synthesis A cell translates a mRNA message into polypeptide with two additional types of RNA transfer RNA (tRNA) ribosomal RNA (rRNA) assembled in complex with polypeptides to form ribosomes
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Overview of Translation 1. Codons of mRNA read through ribosome binding 2. tRNAs act as interpreter between codon and amino acid sequence of polypeptide file://localhost/Users/ssshen/Desktop/17_18TranslationIntro_A.mpg
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v Molecules of tRNA are not all identical Each carries a specific amino acid on one end Each has an anticodon on the other end Translation: Closer Look (Complementary base to codon) (Attach to amino acid & carboxyl group)
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v A specific enzyme called an aminoacyl-tRNA synthetase Joins each amino acid to the correct tRNA Not all 61 tRNAs are synthesized in a cell, typically about 45 tRNAs Due to wobble at 3rd nucleotide AAU AAC AAA AAG Asn Lys Relaxation of complementary base pair rule at 3rd nucleotide A-U/C or U-A/G
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v Ribosomes Facilitate the specific coupling of tRNA anticodons with mRNA codons during protein
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This note was uploaded on 03/28/2008 for the course BIOL 212 taught by Professor Shen during the Spring '08 term at Iowa State.

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Translation - TRANSLATION RNA-directed polypeptide...

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