16 Survey of Biomolecules-Nucleotides and Nucleic Acids

Organic Chemistry: Structure and Function

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1 Survey of Biomolecules Part IV: Nucleotides and Nucleic Acids Lecture Supplement: Take one handout from the stage
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2 Final Exam ate: Monday June 11 me: 11:30 AM - 2:30 PM ocation: Last name A-Ne in Ackerman Union Grand Ballroom Last name Ng-Z in Moore 100 opics: Part A: Noncovalent Molecular Forces through Nucleic Acids X-ray Crystallography not included Part B: Comprehensive uff to bring Pen, pencil, eraser, models Picture ID required Self-addressed 8.5 x 11” envelope, 3 x 41 cent stamps, for exam return ocused Problem Solving Session - Hosted by Rich Saturday June 9, 1:00-2:50 PM, La Kretz 110 email problem suggestions to richbrodriguez@yahoo.com 11” 8.5” Name Address
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3 Early History 9 : Friedrich Miescher isolates “nuclein” from white blood cells y 20 th century : Nuclein found to consist of three fundamental components Phosphoric acid O P HO OH OH X = OH, D -ribose X = H, 2-deoxy- D -ribose CHO H X H OH H OH CH 2 OH Heterocyclic base Heterocycle : has a least one ring which includes an atom other than carbo Pyrimidines Cytosine (C) Thymine (T) Uracil (U) RNA Purines Adenine (A) Guanine (G) N N N N N N H N N H O NH 2 N N H O O H 3 C H N N H O O H N N N N H H O NH 2 N N N N H NH 2
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4 Adenosine (nucleoside) O X HO HO N N N N NH 2 Nucleosides and Nucleotides 0’s :
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16 Survey of Biomolecules-Nucleotides and Nucleic Acids -...

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