Chapter_24.ppt - Chapter 24 Antiparkinsonism Agents Copyright \u00a9 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Parkinson\u2019 s Disease \u2022

Copyright © 2017 Wolters Kluwer • All Rights Reserved Parkinson’ s Disease Parkinson’ s Disease • Progressive chronic neurological disorder • Deficient levels of dopamine • May develop in people of any age • Usually effects those who are past middle age and entering their 60s • No cure for the disease • Therapy is aimed at management of signs and symptoms • Surgery been effective in some for treatment

Copyright © 2017 Wolters Kluwer • All Rights Reserved Progression of Parkinson’ s Disease Progression of Parkinson’ s Disease • Lack of Coordination • Rhythmic Tremors • Rigidity/Weakness • Trouble Maintaining Position or Posture • Bradykinesia • Difficulty Walking • Drooling and Affected Speech • Mask-like Expressions •

Copyright © 2017 Wolters Kluwer • All Rights Reserved Theories About the Cause of Parkinson’ s Disease Theories About the Cause of Parkinson’ s Disease • Viral Infection • Blows to the Head • Brain Infection • Atherosclerosis • Exposure to Certain Drugs • Environmental Factors

Copyright © 2017 Wolters Kluwer • All Rights Reserved Management of Care for Patients with Parkinson’ s Disease Management of Care for Patients with Parkinson’ s Disease • Encourage Patients To: – Be as active as possible – Perform exercises – Maintain independency with ADL’s as long as possible – Follow drug protocols • Caregivers Should: – Monitor adverse effects – Provide encouragement and support

Copyright © 2017 Wolters Kluwer • All Rights Reserved Across Lifespan Across Lifespan • Children-safety and effectiveness for most drugs not been established, occurs rarely in children, if needed diphenhydramine drug of choice. • Adults- require extensive teaching, support and coping, Vitamin B 6 pose serious problem, Pregnancy/Breast Feeding • Elderly- drugs aggravate glaucoma, BPH, constipation, cardiac problems, COPD, follow up visits required for monitoring