Chapter_24.ppt - Chapter 24 Antiparkinsonism Agents Copyright \u00a9 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Parkinson\u2019 s Disease \u2022

Chapter_24.ppt - Chapter 24 Antiparkinsonism Agents...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 24: Antiparkinsonism Agents Chapter 24: Antiparkinsonism Agents
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Parkinson’ s Disease Parkinson’ s Disease Progressive chronic neurological disorder Deficient levels of dopamine May develop in people of any age Usually effects those who are past middle age and entering their 60s No cure for the disease Therapy is aimed at management of signs and symptoms Surgery been effective in some for treatment
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Progression of Parkinson’ s Disease Progression of Parkinson’ s Disease Lack of Coordination Rhythmic Tremors Rigidity/Weakness Trouble Maintaining Position or Posture Bradykinesia Difficulty Walking Drooling and Affected Speech Mask-like Expressions
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Theories About the Cause of Parkinson’ s Disease Theories About the Cause of Parkinson’ s Disease Viral Infection Blows to the Head Brain Infection Atherosclerosis Exposure to Certain Drugs Environmental Factors
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Copyright © 2017 Wolters Kluwer • All Rights Reserved The Degeneration of Neurons that Leads to Parkinson’ s Disease The Degeneration of Neurons that Leads to Parkinson’ s Disease
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Management of Care for Patients with Parkinson’ s Disease Management of Care for Patients with Parkinson’ s Disease Encourage Patients To: Be as active as possible Perform exercises Maintain independency with ADL’s as long as possible Follow drug protocols Caregivers Should: Monitor adverse effects Provide encouragement and support
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Goals of Therapy in Treating Parkinson’ s Disease Goals of Therapy in Treating Parkinson’ s Disease
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Use of Antiparkinsonism Agents Across the Lifespan Use of Antiparkinsonism Agents Across the Lifespan
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Across Lifespan Across Lifespan Children-safety and effectiveness for most drugs not been established, occurs rarely in children, if needed diphenhydramine drug of choice. Adults- require extensive teaching, support and coping, Vitamin B 6 pose serious problem, Pregnancy/Breast Feeding Elderly- drugs aggravate glaucoma, BPH, constipation, cardiac problems, COPD, follow up visits required for monitoring
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Dopaminergic Dopaminergic Actions
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