Lecture_twenty_four - 1 FIANL EXAM CONFLICT Friday December...

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2 FIANL EXAM CONFLICT Jessica Miller Brett Diffin Yelena Kleshchik Laura Van Putten ** Kristina Rose ** Dina Valeeva ** Friday December 7th 3:00pm to 5:00pm at E100. Make-up exam: Thursday (Dec13th) 10:00am-noon
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3 The Eukaryotic Genome and Its Expression Chapter 14
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4 I. The Eukaryotic Genome Key differences between eukaryotic and prokaryotic genomes: 1.Eukaryotic genomes are larger. - We Many cell types that must be maintained (multicellular), hence more genes, more regulatory proteins. 1.Much of eukaryotic DNA is noncoding. - That is, no production of mRNA/RNA The lily has 18 times more DNA than a human.
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5 1. Eukaryotes have multiple chromosomes. As a consequence: Each chromosome needs, replication origins, cenetromere, and telomeric regions. 1. In eukaryotes, translation and transcription are physically separated which allows many points of regulation before translation begins.
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6 Regulation
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7 (e.g. Histones) (For regulation) (Part of mRNA processing) (Part of mRNA processing)
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8 Yeast, Saccharomyces cerevisiae Nematode (roundworm), Caenorhabditis elegans Fruit fly, Drosophila melanogaster Thale cress, Arabidopsis thaliana II. Eukaryote model organisms Just as we used virus and bacterial (prokaryotic) models to understand the very basics of gene expression, we us the following advanced models to understand our system’s greater complexity.
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Yeast ( Saccharomyces cerevisiae ) is a single celled eukaryote. Has Compartmentalization into organelles which requires more genes than prokaryotes have. Yeast has 16 chromosomes; haploid content of 12 million base pairs (bp). A. Yeast
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This note was uploaded on 03/29/2008 for the course CEM 251 taught by Professor Rathke during the Spring '07 term at Michigan State University.

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Lecture_twenty_four - 1 FIANL EXAM CONFLICT Friday December...

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