{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

NS 132 SQ 8 - Lipids in Chronic Disease(CHD& CA Study...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Lipids in Chronic Disease (CHD & CA): Study Questions Synopsis : This lecture addresses the role ō lipids in chronic disease; specifically with regard to Coronary Heart Disease (CHD). First, we'll study the incidence, pathology & etiology ō CHD. Next, the impact ō lipid levels & their associated risk as well as diet & serum lipids will be explored. Practical, actionable diet recommendations conclude the topic. Synopsis : This lecture examines what we know about the role ō lipids in the development ō cancer. On this issue we explore areas ō scientific consensus as well as disagreement. Concluding the lecture are specific diets (American, Asian & Mediterranean) & their correlation to cancer incidence. Textbook readings : Chapter 5 Coronary Heart Disease (CHD) I. Incidence a. Leading cause ō death in US b. Half ō CHD deaths at >65yr c. Began to increase ~ 1920 d. Peaked at 328 per 100,000 in 1965 e. 236 per 100,000 in 1983 Incidence What is the second major cause ō death in the US (after cancer)? Coronary Heart Disease (CHD) : disease caused by atherosclerosis that results in narrowing & thickening ō arterial walls leading to insufficient blood flow to heart muscle & possibly resulting in heart attack After cancer, heart disease (CHD) is the 2 nd major cause ō death in US. Is CHD a disease ō older or younger people? CHD is a disease ō older people.- 50% : > 65 yrs (common) What are the trends in CHD? Is it increasing or decreasing? Trends in CHD :- Increased around 1920 or so (end ō WWI)- Peaked in 1965 at 328 deaths/100,000 pop.- Dropped to 236 deaths in 1983- Decline at slower rate ( decreasing ) due to better (ER) & more treatment, prevention, & less smoking II. Pathology [Artherosclerosis ] a. Thickening & narrowing ō arterial walls b. Plaques - invasion ō cholesterol into intima c. Diminishes circulation or blocked by clot d. Clot formed by hemorrhage ō plaque or elsewhere [Road to a heart attack ] e. Ischemia cases MI or stroke (cerebrovascular accident) f. Begins at early age Pathology : study ō disease processes Atherosclerosis What is atherosclerosis? What happens to artery walls? atherosclerosis : thickening & narrowing ō artery walls caused by cholesterol invasion ⇒ plaque formation- process by w/c cholesterol is deposited in arterial plaques, gradually thickening artery walls & narrowing arterial passage- process by w/c cholesterol from LDL is deposited in arterial walls, resulting in thicker wall & narrower passage for blood- High levels ō LDL cholesterol contribute to atherosclerosis. What are plaques? What are they formed ō? Where do they occur? Plaques are invasion ō cholesterol into arterial walls . What do plaques do to circulation? What happens when plaques & blood clots interact? Where are these clots formed?...
View Full Document

{[ snackBarMessage ]}

Page1 / 11

NS 132 SQ 8 - Lipids in Chronic Disease(CHD& CA Study...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online