NS 132 SQ 18 - Phytochemicals: Study Questions Synopsis:...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
Phytochemicals: Study Questions Synopsis : Phytochemicals are considered non-nutrients. In humans, a deficiency ō essential nutrients will reveal itself through disease symptoms. That is not the case w/ phytochemicals. Yet research continues to reveal the critical role phytochemicals or “plant chemicals” play in chronic disease prevention. This lecture examines what we know to date about the relationship ō phytochemicals to cancer & to other chronic diseases. We also examine the role phytochemicals play w/in plants. Dietary recommendations, as always, conclude the lecture. Textbook readings: pp. 36-37, 194-195 I. Overview a. b. Phytochemicals are non-nutrient - role in chronic disease prevention i. Plant chemicals a. F/V protective effect against cancer b. Protective for particular cancer sites c. Those who eat the least F/V have at least double the cancer risk ō those who eat the most d. Protective e. View ō nutrients as responsible mechanism (for protection) f. View ō Vitamin A as protective factor g. Vitamin A precursor as protective factor h. Carotenoids i. Beta-carotene trials j. Phytochemicals k. Carcinogenesis (process by which cancer develops) l. 3-stage model ō cancer (carcinogenesis) m. 2 qualities for malignant tumor (vs. benign) n. Prevention o. Treatment against cancer? How solid is the evidence? Yes , epidemiological studies found fruits & vegetables to be protective against cancer. The evidence is very solid —128/156 studies showed protective effect. - well-studied & wide agreement - strong evidence : F/V have protective effective against cancer. - also How much greater is the risk ō cancer for those people who eat the fewest Those who eat fewest F/V at least double risk ō cancer than those who eat most F/V. - ↑ risk almost always underestimated
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
- cancers : lung , esophagus, colon , bladder, cervix, ovary, endometrial, breast , pancreas, stomach, prostate Some protective F/V : lettuce, dark leafy greens (chale, collard greens, mustards, broccoli, cauliflower, turnip, rutabaga), onions, carrots, cabbage family, potatoes, citrus Nutrients as responsible/protective mechanism vitamin A, it was postulated that vitamin A might be the protective agent. Why? prevention treatment? - F/V: good sources ō vit. A, retinol ( e.g. dark leafy greens, yellow/orange F/V) - beta carotene –converted into→ retinol (protective against cancer?) - retinol : role in cell differentiation Vitamin A as protective factor Are cancer cells well differentiated? What do we mean by cell differentiation? How does vitamin A affect cell differentiation? But do blood levels ō A correlate well w/ cancer risk? No
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

Page1 / 9

NS 132 SQ 18 - Phytochemicals: Study Questions Synopsis:...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online