PSB-QUIZ 5 notes (4).docx - CHAPTER 16 Alzheimer’s...

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CHAPTER 16 Alzheimer’s Disease: Burning Out With Age? - Alzheimer Disease : The most common form of Dementia in the world today. - Alzheimer Disease also known as Alzheimer’s dementia. -About 24 million people worldwide suffer from this disorder. - Alzheimer Disease- Begins with an early or “ prodromal ” form known as mild cognitive impairment. -Mild cognitive impairment includes -minor or nondisabling problems with memory -spatial navigation and language. In each year passing Alzheimer progresses steadily. The core deficit in Alzheimer progressive impairment of Episodic memory. - The term Executive functions -such as planning -reasoning -problem solving -judgment also deteriorate steadily. Spatial navigation difficulties may leave a patient prone to getting lost or wondering. Anomia- language difficulties(word-finding difficulty). Aphasia- a more severe impairment in language production or comphrension. Alzheimer is a disease of the aging of the brain. - late in the illness cause patients to require help even with basic activities such as -feeding -showering
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-using the bathroom Patients with Alzheimer’s disease typically survive 7-10 years from the time of initial diagnosis. Alzheimer is uncommon before the age 60. -At 65, 1% of people have the disease. -At 75, the rate increases to 10-15%. -At 85, the rate reaches nearly 40%. QUESTION 1: what enables some people to escape this debilitating illness whereas others fade slowly into their “ second childhood”? -Answer: Today with more and more people living into their 80’s and 90’s and beyond, the race is on to discover ways of preventing and treating the disease. QUESTION 2: what is the cause of the dementia we see in Alzheimer’s disease? -Answer: Alzheimer discovered that patients cerebral cortex was cluttered with abnormal debris now known as amyloid plaques and neurofibrillary tangles. -German neuropsychiatrist Alois Alzheimer studied the brain of a patient who died with senile dementia. -Abnormalities such as amyloid plaques and neurofibrillary tangles do not appear throughout the entire cortex, but are more densely concentrated in some of the association areas of the brain: the inferior parietal lobe, medial parietal lobe, medial frontal lobe, medial temporal lobe, and in particular , the frontal lobes and posterior cingulate cortex.
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  • Summer '16
  • Anthony Dick

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