UWorldMCATPssgOrgChemnr2Dec2016.pptx - Question Information...

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Question Information Q-Bank Sim Subject Foundation Validity Author(s) Reviewer(s) Editor(s) Passage Stem MCAT Non-Sim Organic Chemistry Reyes, V. M. OCHM – Organic Synthesis 5 years 0000000 0000000 Synthetic organic chemistry is arguably the most important and most active branch of organic chemistry, and a casual inspection of the chemical literature will attest to that. Synthetic organic chemists are especially in high demand in the drug discovery and manufacturing as well as the big bio-pharma industries. Organic reactions named after their discoverers (“named organic reactions”) alone number a few hundred, and most of them are intended for the synthetic route to novel organic compounds. Synthetic organic reactions involve the formation of new covalent bonds usually involving C-atoms and the reassembly of old ones. The product is usually an organic molecule larger than the reactants involved, and ready for the next synthetic reaction. The ultimate aim is the creation of a new drug or material for specialized purposes (e.g., biomaterials, etc.). In this module, shall focus on the Diels-Alder reaction, an important and time-tested way to create cyclic organic compounds. Passage Information Media ID(s) Passage ID
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The Diels-Alder reaction is a reaction between a conjugated diene (a.k.a., 1,3-diene) and an alkene (a.k.a. olefin ), or sometimes an alkyne (a.k.a. acetylene), to form a 6-
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