Week 4 main discussion post.docx

Week 4 main discussion post.docx - Week 4 main discussion...

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Week 4 main discussion post Description of the case that you selected. Substance abuse research studies encounter ethical issues and confidentiality issues routinely when implementing and evaluating studies for research. The study that I chose was a study that enrolled opioid addicts that were currently using suboxone to treat their opioid addiction for greater than three weeks. Opioid users are at greater risk of developing HIV/AIDS due to IV drug use. This study proposed to take healthy HIV/AIDS-free individuals and test a new drug called Kaletra, a commonly used antiretroviral therapy . The subjects in question would all admit to the hospital for an overnight stay to have baseline blood work done including Suboxone levels. They were then administered Kaletra during the hospital stay. These subjects would continue to be monitored in an outpatient program with daily doses of both Suboxone and Kaletra. At the end of the fourteen days, the subjects would re-admit to the hospital to have blood work drawn to measure levels of both Suboxone and Kaletra (Yale University, 2018). The purpose of this study was to test another opioid maintenance drug in place of Methadone. Methadone has long been the choice for long-term maintenance treatment of opioid addiction. But Methadone also interacts with many medications and causes side effects some very serious. Some of these medications include antiretroviral therapy medications for HIV/AIDS. Because HIV/AIDS patients also can be opioid addicts they need treatment for both disease processes which cannot occur with the use of Methadone. This test replaces Methadone and uses Suboxone to see if there are any side effects related to using both medications simultaneously to treat dual diagnosis (Yale University, 2018). At the completion of the study, the researchers planned to compensate each subject $1000 for completing the study in its entirety, but subjects would receive no payment unless they completed all study interventions. The researchers allowed for a pro-rated payment schedule only for subjects forced to withdraw secondary to adverse events.
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  • Fall '16
  • Morphine, Yale

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