BS110 Lecture 3 - What is the architecture of genetic...

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Unformatted text preview: What is the architecture of genetic information? What do genes do? Friday Jan 18, 2008 Last Time A lot of words to explain DNA structure Today, more about how DNA replicates and what it does How do organisms grow? Repair themselves? Must make new cells. Need to have same blueprint in all cellstherefore, DNA need to replicate so that each daughter cell can have the entire blueprint in it Cell cycle Involves several phases, that allow for growth, DNA replication, and seperation into 2 new, identical (well, almost) daughter cells Mitosis: growth Mitosis Cell Cycle Mitosis: asexual reproduction Cell Cycle Where are chromosomes replicated? Unreplicated? Human Genome: Two Stages of Representation A B 32 12 46 60 48 4 - 45? G1: Cells DNA is unduplicated f F G2: Cells DNA is duplicated f F f F Metaphase f F f F f F f F Metaphase f F f F Sister chromatids separate: 1 copy to each daughter cell Metaphase - Anaphase f F f F f F f F Sister chromatids separate: 1 copy to each daughter cell t f F T T t F f n Ploidy sisters homologs Q Q q q What is the actual cellular machinery of DNA replication? DNA Replication Step 1: Enzymes break bonds between bases helix unwinds, exposing free bases SPSPSPSP...
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BS110 Lecture 3 - What is the architecture of genetic...

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