WEEK 1 NURS 6501 Week 1 Discussion Initial post Factors that Influence Disease: Atherosclerosis A forty-six-year-old woman comes to the emergency room complaining of pain when walking, weakness of the left arm that happens often. The stated that these symptoms started about three months earlier and are not getting better. She also claims of short of breath when exercising. The patient says that the mother had atherosclerosis and died at the age of fifty-three. In an article in NIH (2018), found that atherosclerosis is the result of hyperlipidemia and lipid oxidation, it’s a disease in which all the vascular system from aorta to coronary arteries can be involved. Nurse practitioners (NPs) are expected to know factors associated with any disease to be able to manage it. As such, NPs to manage the disease process have to correctly diagnose the patient and know (1) what a patient would complain of, (2) what to look for in a physical exam, (3) diagnostic tests needed to confirm preliminary prognosis, (4) types of therapies essential to treat a diagnosis, (5) information necessary in educating the patient, and (6) outcomes to evaluate the effectiveness of medical interventions (Laureate Education, Inc. (Executive Producer), 2012d). Genetics “Understanding pathophysiology also entails the utilization of principles, concepts, and basic knowledge from other fields of study including pathology, genetics, epigenetics, immunology, and epidemiology” (Huether and McCance, 2017, p. xii). Knowledge how genes are passed down from one generation to the next can disclose considerable amounts of
information about disease-causing genes, revealing treatment options, or genetic counseling. Utilizing a pedigree chart, which depicts family members affected by a genetic disease and summarizes family relationships is one tool in tracking transmission of a genetic disease (Huether and McCance, 2017). Individuals are at risk for Atherosclerosis due to genetics have a family history of hypertension, high cholesterol, early heart disease, or have elevated levels of C- reactive protein (CRP) because CRP is a sign of inflammation in the body (National Institutes of Health (NIH), 2016). Atherosclerosis When plaque (fatty deposits) clogs your arteries, that’s called atherosclerosis. These deposits are made up of cholesterol, fatty substances, cellular waste products, calcium and fibrin (a clotting material in the blood). Arteriosclerosis is the thickening and hardening of blood vessel causing lesions on the endothelial lining of a blood vessel wall (Huether and McCance, 2017). Plaque is the formation of lesions from the accumulation of lipid-laden macrophages on the artery wall and is an injury to the endothelial cells lining the arterial walls (2017). Plaque may cause damage with enough accumulation, causing obstruction with thrombosis resulting in tissue infarction often seen in transient ischemic events or stroke, or in coronary artery disease leading to myocardial ischemia; furthermore, any area of the body may be affected by atherosclerotic lesions (2017).
- Spring '15
- The Bear