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BIOLOGY 2 Question 6.2 Write two article reviews from sites of your choosing. One subject should concern occupational safety and one should be on the latest findings on the causes and possible treatment of Alzheimer’s disease. (Article Reviews) (20 points) Review on Alzheimer's disease, its causes and possible treatment Alzheimer’s disease is said to be a destructive neurodegenerative disorder that is characterized by these major groups of symptoms that include: cognitive dysfunction, psychiatric symptoms and behavioral disturbances, and difficulties in performing daily living activities (McKhann and Drachman, 1984). The possible causes of Alzheimer’s disease are not well known up to date but case control studies have linked some risk factors with the disease that include; family history, apolipoprotein status, hypertension, genes, Down’s syndrome, physical activity level, alcohol consumption, mood disorders, nutritional supplement intake and hypercholesterolemia. (McKhann and Drachman 1984). The signs and symptoms of Alzheimer’s disease include; neuropsychiatric symptoms such as apathy, depression, violence, anxiety, sleep interruption, psychosis and delusions. However, memory loss is the first symptom that is noticed, this occurs gradually and it may lead to misattribution to ageing. The onset is insidious, emerging with severe loss of memory with difficulty in word finding (Winblad et al. 2016). Alzheimer’s disease is clinically diagnosed by following the following logical sequences: a mental state assessment that includes validated cognitive function test, and the physical examination focuses on vascular and neurological signs that are supplemented by investigations.
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BIOLOGY 3 In most cases, treatment of Alzheimer’s disease involves many psychological interventions for clinical syndrome regardless of its cause. In non-clinical interventions, non- drug interventions are tried first mostly when the symptoms are neither causing distress nor placing the patient at risk of themselves or others. Therapeutic interventions are used to the individuals in order to establish a good rapport between the patient and those taking care of him (Winblad et al. 2016). The recent advances in treating Alzheimer’s disease involves a process called anti- amyloid therapy. This involves the use of drugs with different mechanisms of actions Finally, there are significant active researches that are going on in the development of new inhibitors for BASE, kinase and y-secretase as targets for treatment of Alzheimer’s disease. Thus, it is hoped that all the ongoing researches, combined should lead to a clearer understanding of the progressions that happen in the Alzheimer’s disease. Thus, I conclude that these possible treatments that I have discussed of Alzheimer’s disease are also potentially targeted for research and development for the treatment of the disease. (Winblad et al. 2016).
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  • Fall '16
  • dfds sff
  • Occupational safety and health

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