lecture_15_genetic_eng

lecture_15_genetic_eng - Genetic Engineering Matt Ferkany...

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Genetic Engineering Matt Ferkany IAH 206
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A Question Are there gene technologies we should forbid or limit the use of?
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Some background to the question Social: eugenics Scientific/medical Ethical considerations
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Scientific background Gregor Mendel: Discovered laws of heredity from experiments with peas plants Wilhem Johannsen: proposed the concept of genes in 1909 Genes: a unit of DNA that functions as instructions for building the body and that is heritable
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Scientific background Watson and Crick: discovered the ‘double-helix’ stru in 1951 Genetic engineering
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Recent scientific developments 1990-2003: Human Genome Project Mapped gene-chromosome sequence DNA sequencing of genes
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Some applications of gene tech Industrial: bacteria to manage industrial waste and pollution Agricultural: Genetically modified plants resistant to disease, frost, insects Medical: Recombinant DNA produces vaccines, insulin Diagnostic: genetic screening of fetuses for Huntington’s Disease, PKU, predispositions to cancer, Alzheimer’s Reproduction: in vitro fertilization, cloning Somatic and germline gene therapy of genetic disease: Somatic: affects only existing person, not passed on Germline: changes that will be passed on
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Question Should we allow germline changes to human beings, or only somatic changes?
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Social background: Eugenics Eugenics: “well born”; the study of human hereditary improvement through genetic control Positive eugenics: attempts to produce and reproduce desirable genes Negative eugenics: attempts to eliminate undesirable genes
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This note was uploaded on 03/30/2008 for the course IAH 206 taught by Professor Staff during the Spring '08 term at Michigan State University.

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lecture_15_genetic_eng - Genetic Engineering Matt Ferkany...

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