Chapter 25 Notes.docx - Chapter 25 Notes Blood and...

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Chapter 25 Notes: Blood and Lymphatic InfectionsCirculation of Blood and LymphoSupplies nutrients and O2to cells, removes wasteAlso heats, cools to maintain optimum temperatureInfections can be serious, since infectious agents can becomesystemic, orcarried throughout bodyConditions named after infectious agentBacteremia, viremia, and fungemiaAnatomy, Physiology, and EcologyoCardiovascular system and lymphatic system normally sterileBacterial Diseases of the Lymphatic and Blood Vascular SystemoNot common; can kill quickly or proceed slowlyUsually bacteria carried into bloodstream by flow of lymph from area of infection in tissuesEndocarditisis infection of heart valves or surfacesSubacute bacterial endocarditisusually caused by organisms withlittle virulence, proceeds more slowlySepsisis caused by both Gram-negative and positive bacteria, also other infectious agentsAcute bacterial endocarditisstarts suddenly with feveroSubacute Bacterial Endocarditis (SBE)Signs and SymptomsNoticeable fatigue, slight fever Typically become gradually ill and slowly lose energy over weeks or monthsCausative AgentUsually normal microbiota of mouth or skin such as Streptococcus viridans and Staphylococcus epidermidisPathogenesisBacteria enter blood during dental procedures, tooth brushing, or trauma; can get trapped in thin blood clots that form around deformed heart valvesMultiply, form protective biofilmPieces of infected clot can break off, block important blood vessels, lead to tissue deathTreatment and PreventionLong term antibacterial medicationArtificial implants often must be replacedNo methods to preventoSepsis and Septic ShockSigns and SymptomsSevere sepsis results in violent shaking, chills, fever
If septic shock develops, urine output drops, respiration and pulse increase, arms and legs become coolCausative Agents

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