MMG 301 Study Guide L30.31

MMG 301 Study Guide L30.31 - MMG 301 Final Exam Study Guide...

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MMG 301 Final Exam Study Guide Lecture 30/31: Pathogen: any disease-producing organism (opportunistic microorganism). Pathogenicity: the ability to produce pathologic changes or disease. Virulence: the quantitative measure of pathogenicity; the degree of pathogenicity displayed by a pathogen. Infection: the growth of microbes/organisms inside the host tissues; colonization. Normal Flora: a mixture of microbes normally found at any anatomical site in a healthy organism. Resident Flora: (colonizing)- flora consistently found on skin Transient Flora: (contaminating)- flora do not colonize or persist; do not survive for extended periods on skin. Exotoxins: proteins that are released extracellularly by a microorganism as it grows that produce immediate host cell damage. Enterotoxins: proteins that are released extracellularly by a microorganism as it grows that produce immediate damage to the small intestine of the host; exotoxins that exert their effect in the small intestine Endotoxins: the lipopolysaccharide portion of the cell envelope of certain gram-negative Bacteria , which is a toxin when solubilized. Nosocomial Infections: an infection that is contracted in a hospital or health-care setting. Bacteremia: the presence of microorganisms in the blood; occurs when there is enough growth that viable bacteria enter the circulating bloodstream or lymphatic system. Septicemia: the presence of bacteria, or their toxins, in the blood. Bacterial Interference: when normal flora protect the host from colonization by pathogenic microorganisms. Disease: an abnormal condition of an organism that impairs bodily functions; damage or injury to the host??? Gnotobiotic: “known flora”--- gnotobiotic animals: animals born in germ-free environment and microbiologically monitored. This allows investigation of interactions with specific microorganisms deliberately introduce into the animal. Hyaluronidase: an enzyme virulence factor that breaks down polysaccharide that glues host cells together. Collagenase: an enzyme virulence factor that breaks down collagen in connective tissues. Coagulase:
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MMG 301 Study Guide L30.31 - MMG 301 Final Exam Study Guide...

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