image.jpg - `meiosis central Dogma Regulation of landing D X` ist Many Proteins work together in DNA replication 909{` and repair Base pairing to a

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Unformatted text preview: `meiosis central Dogma Regulation of landing D X` ist . Many Proteins work together in DNA replication 909 {` and repair Base pairing to a template Strand . - Since 2 Strands OF DNA are complementary, each Strand acts as a template for building a new strand in replication - in DNA replication, the parentmolewie unwinds and two new daughter strands are built based on base pairing rules bwatson & crick's model was semiconservative predicted that when a double helix replicates, each daughter molecule. Will have one old strand and one new strand DNA Relication - replication begins at origins of replication where the 2 DNA Strands are separated, opening up a replication " bubble "\ Replication proceeds in both directions from each origin , until entire* molecule is copied at the end of each replication bubble is a replication fork, Y shaped region where new DNA strands are elongating\ Helicases\ enzymes that untwist the double helix at the replication |forks \Single - Strand landing Proteins, bind to and stabilize single stranded DNA * Topoisomerase corrects " over whinding's a head of replication forks by breaking , swiveling Srejoining DNA strands\ . DNA polymerase cannot initiate synthesis of a Poly nucleotide Job is to add nucleotides to the growing molecule - they can only add nucleotides to the 3' end `Polymerase : add new nucleotides to existing nucleotides & Cannot start a new molecule \Primuse, Can start an RNA chain from scratch. adds RNA nucleotides one at a time using parental DNA as a template 5 DNA 31 5' 5 7...
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  • Fall '15
  • Eric Martin
  • DNA, template strand, bwatson & crick

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