ONDANSENTRON .docx - 1 Medication Order ondansetron HCl 4...

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1) Medication Order: ondansetron HCl 4 mg Q4 hr PRN IV 2) generic name: ondansetron hydrochloride 3) Trade name: Zofran 4) Maximum Safe Dose in 24 hours: 8 mg 5) Therapeutic class/Pharmacologic classification: Antiemetics / Selective serotonin (5-HT 3 ) receptor antagonists 6) Indication: To prevent postoperative nausea and vomiting from highly emetogenic chemotherapy 7) Black Box Warning: N/A 8) Common Adverse Reactions: dizziness, fatigue, headache, fever, agitation, anxiety, chest pain, constipation, diarrhea, pruritus, chills. 9) Life Threatening Adverse Reactions: arrythmias, Hypoxia. 10) Drug-Drug Interactions: Apomorphine, Cimetidine, phenobarbital, rifampin, antiarrhythmics, antipsychotics, antidepressants, SSNRIs, SSRIs. 11) Food-Drug Interactions: N/A 12) Nursing Considerations : a) Assess: Assess for nausea, vomiting, abdominal distension, and bowel sounds prior and following administration. Assess patient for extrapyramidal effects periodically. Alert: Correct electrolyte abnormalities ( hypokalemia or hypomagnesemia ) before infusing drug. b) Administration: IM, Document injection site.
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  • Fall '15
  • Sandra Rodriguez
  • Chemotherapy, Cardiac electrophysiology, Long QT syndrome, Ondansetron, Short QT syndrome

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