NSG 6005 Week 5 project.pptx - PHARMACOLOGICAL TREATMENT OF DEEP VEIN THROMBOSIS(DVT ROBERT VEROS NSG 6005 SOUTH UNIVERSITY ONLINE DEEP VEIN THROMBOSIS

NSG 6005 Week 5 project.pptx - PHARMACOLOGICAL TREATMENT OF...

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PHARMACOLOGICAL TREATMENT OF DEEP VEIN THROMBOSIS (DVT) ROBERT VEROS NSG 6005 SOUTH UNIVERSITY ONLINE
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DEEP VEIN THROMBOSIS A thrombus (blood clot) that attaches and remains in the wall of a vessel. A DVT normally refers to a thrombus formation in a large vessel, usually of the lower extremities. They are more prevalent in venous circulation due to lower pressure. Approx. 900,000 venous thrombosis events (VTEs) occur annually. Approx. 1/3 have been fatal (McCance, 2014)
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DEEP VEIN THROMBOSIS RISK FACTORS There are three factors known as the triad of Virchow that attribute to DVTs. Damage to the endothelial Trauma Medications Venous stasis Obesity Immobility (hospitalization, bedridden) Leg dependency for prolonged amount of time (long trips)
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DEEP VEIN THROMBOSIS RISK FACTORS Venous stasis cont. Age Heart Failure Hypercoagulable disorders Malignancy Genetic disorders Oral contraceptives and hormonal replacement therapy Pregnancy Anti-phospholipid syndrome (McCance, 2014)
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CLINICAL MANIFESTATIONS Clotting factors and platelet aggregation lead to thrombus formation. Further platelet aggregation growth continues due to inflammation around the clot. If clot grows and causes obstruction to the vessel impeding blood flow. Causing Edema Redness Pain Ulceration (McCance, 2014)
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PHARMACOLOGICAL TREATMENT OF DVT Anticoagulants Heparin and Low-Molecular-Weight Heparins (LMWH) Heparin Dalteparin Enoxaparin Tinzaparin Fondaparinux Warfarin (Woo & Robinson, 2015)
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PHARMACOLOGICAL TREATMENT OF DVT Antiplatelets Aspirin Clopidogrel Tricagrelor Ticlopidine Rivaroxaban
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  • Fall '16
  • Thrombosis

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