Practice exam 2 - Exam 2 Genetics BIOL 2004 CRN 90827 4...

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Exam 2 Genetics BIOL 2004 CRN 90827 4 October 2007 1. Which of the following is one reason for the reduced fertility of monosomic individuals? (1) Higher frequency of recombination involving the monosomic chromosome (2) Formation of gametes lacking a copy of the monosomic chromosome (3) Formation of gametes carrying two copies of the monosomic chromosome 2. Which of the following accurately describes the human genotype? (1) 22 pairs of autosomes and a pair of sex-determining chromosomes (2) 46, XX (female) or 46, XY (male) (3) 46 pairs of autosomes and either 2 X chromosomes (females) or 2 Y chromosomes (males) (4) All of the above (5) Answers (1) and (2) (6) Answers (2) and (3) 3. Inversions: (1) increase recombination between genes flanking the inversion (2) decrease recombination between genes flanking the inversion (3) have no effect on recombination, the same DNA is between the flanking genes 4. You have been hired by the International Olympic Committee to be the sex determination expert for the Sydney Olympics. Rather than carry out expensive and time-consuming karyotyping of chromosomes at metaphase, you remember a test involving a "Barr Body". Which of the following statements is correct concerning the use of the "Barr Body" in sex determination in humans? (1) The Barr Body is the inactivated Y chromosome that lacks genes (2) The Barr Body is one of the 2 female X chromosomes (3) The Barr Body is seen only in germ line tissue (testes and ovary) (4) Normal males have one Barr Body in the nucleus (5) Normal females have one Barr Body in the nucleus (6) Answers (1) and (4) (7) Answers (2) and (5) (8) Answers (1), (3), and (5) 5. Which of the following are examples of chromosome rearrangements? (1) Deletion (2) Duplication (3) Inversion (4) Translocation (5) All the above (6) None of the above, they are only found in transposons 6. What type of bond is responsible for the association between nucleic acids in opposite strands of DNA? (1) Ionic bonds (2) Hydrogen bonds (3) Covalent bonds (4) Interest-free bonds (5) Hydrophobic bonds 7. Unequal recombination can result in which of the following chromosome abnormalities? (1) Only inversion (2) Only deletion (3) Only duplication (4) Inversions and disjunctives (5) Deletions and duplications 1
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Answers for questions 8-11 (1) Conjugation (2) Transformation (3) Transduction (4) Transcription (5) Conjunction 8. Gene transfer mechanism in bacteria susceptible to inhibition by DNase. (2) 9. Gene transfer mechanism in bacteria that can result in transfer of the entire bacterial chromosome. (1) 10. Gene transfer mechanism requiring the presence of the F-plasmid in the donor cell. (1) 11. Gene transfer mechanism that relies upon mistakes in packaging DNA in bacteriophage. (3) 12. Which of the following is the sequence complementary to: 5’-ATGCATGCAATTGC-3’? (1) 3’-ATGCATGCAATTGC-5’ (2) 3’-TACGTACGTTAACG-5’ (3) 5’-TACGTACGTTAACG-3’ (4) 5’-CGTTAACGTACGTA-3’ 13. Dr. Mary Lyon discovered "dosage compensation of X-linked genes" in mammals. Which of the following describes "dosage compensation of X-linked genes"?
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