Genetics Practice Exam 3

Genetics Practice Exam 3 - Genetics EXAMINATION 3 BIOL 2004...

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Genetics BIOL 2004 CRN 90827 EXAMINATION 3 Tuesday, 30 October 2007 Chapters 12, 13, 14, and 15 1. Which of the following are activities of DNA polymerase? (1) 5’ → 3’ polymerase (2) 3’ → 5’ polymerase (3) 5’ → 3’exonuclease (4) 3’ → 5’ exonuclease (5) 5’ → 3’ligase (6) All the above (7) Answers (1), (3), and (4) (8) Answers (1), (3), and (5) 2. What is the translation initiation codon? (1) 5'-UAG-3' (2) 5'-AUG-3' (3) 3'-AUG-5' (4) 3'-UAG-5' (5) 5'-GAG-3' 3. Which of the following are ways to regulate (i.e., presence or level) proteins produced by cells? (1) The presence of alternative sigma proteins. (2) The length of 3’-poly (A) sequences in mRNA. (3) The presence of introns and ability to create different splicing patterns. (4) All the above 4. Which of the following distinguish DNA from RNA polymerases? (1) RNA polymerases do not require a primer to initiate replication (2) DNA polymerases require a primer to initiate replication (3) RNA polymerases lack 3’ → 5’ exonuclease activity (4) DNA polymerases can utilize both 5’-NTPs and 5’-dNTPs (5) All the above (6) Answers (1), (2), and (4) (7) Answers (1), (2), and (3) 5. What is the function of sigma protein in RNA synthesis? (1) None, it is a protein made up by JOF, III (2) Sigma directs RNA polymerase to the origin of DNA replication (3) Sigma directs RNA polymerase to promoters (4) Sigma is involved in the termination of mRNA synthesis 6. Compared to rRNA and tRNA, mRNA is: (1) more stable. (2) less stable. (3) equally stable. 7. Where does RNA processing occur? (1) In the nucleus (2) In the cytoplasm (3) In both the nucleus (splicing) and cytoplasm [poly (A)]
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(4) Only in vitro , it is a laboratory thing 8. What is the function of the 3’ → 5’ exonuclease activity of DNA polymerase? (1) Degradation of RNA primers in Okazaki fragments (2) Initiation of DNA replication by degrading DNA to form primers (3) Proof-reading newly synthesized DNA (4) RNA editing (5) Answers (2) and (4) 9. Compared to prokaryotes, eukaryotes have: (1) fewer assessory proteins involved in influencing the binding of RNA polymerase to promoters. (2) more assessory proteins involved in influencing the binding of RNA polymerase to promoters. (3) an equal number of assessory proteins involved in influencing the binding of RNA polymerase to promoters 10. The rate of mRNA synthesis is controlled by which of the following? (1) The rate of movement (elongation) of the polymerases on the templates; not the rate of initiation. (2) The rate of initiation of synthesis by binding at the promoter; not the rate of elongation. (3) The rate of degradation of RNA polymerase because the subunits are recycled for synthesis. (4)
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This note was uploaded on 03/30/2008 for the course BIOL 2004 taught by Professor Jofalkinham during the Spring '08 term at Virginia Tech.

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Genetics Practice Exam 3 - Genetics EXAMINATION 3 BIOL 2004...

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