Mechanisms of HibernationALEXIS EARLBIOL 4260012/1/161
OutlineIntroduction to hibernationWhat is hibernationHibernation vs. torporWhat organisms hibernateDown regulation of sodium channels in the central nervous system of hibernating snailsModulation of gene expression in heart and liver of hibernating black bears (Ursus americanus)Hibernation in humans?ConclusionResources2
What is Hibernation?1.Hibernation is the state of inactivity and metabolic depression in endotherms. 2.Characterized by low body temperature, slow breathing and heart rate, and low metabolic rate.3.Term has been redefined to include more animals.4.Hibernation and torpor use similar mechanisms1.Hibernation vs. Torpor5.What kinds of animals hibernateAndrews, M.T. (2011) Advances in molecular biology of hibernation in mammals. PLoS ONE, 23;431-440.3
Down Regulation of Sodium Channels in the Central Nervous System of Hibernating Snails1.