Chapter_02.pptx - Chapter 2 Drugs and the Body Copyright \u00a9 2013 Wolters Kluwer Health | Lippincott Williams Wilkins Pharmacodynamics Pharmacodynamics

Chapter_02.pptx - Chapter 2 Drugs and the Body Copyright...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 2: Drugs and the Body Chapter 2: Drugs and the Body
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Pharmacodynamics Pharmacodynamics Pharmacodynamics is the science of dealing with interactions between living organisms and foreign chemicals. Each living system has chemical reactions occurring continuously in the body. When other chemicals (drugs) are added to the body other effects occur.
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Drug Action Drug Action Replace or act as a substitute for missing chemicals To increase or stimulate certain cellular activities To depress or slow cellular activities To interfere with the functioning of foreign cells
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Receptor Sites Receptor Sites Receptor sites react to certain chemicals to cause an effect within the cell. Agonists Noncompetitive antagonists- Competitive antagonists Drug- enzyme interactions Selective toxicity
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Lock and Key Lock and Key
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Pharmacokinetics #1 Pharmacokinetics #1 The study of absorption, distribution, metabolism (biotransformation), and excretion of drugs
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Pharmacokinetics #2 Pharmacokinetics #2 Onset of drug action Drug half-life Timing of the peak effect Duration of drug effects Metabolism or biotransformation of the drug Site of excretion
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Copyright © 2017 Wolters Kluwer • All Rights Reserved Pharmacokinetics #3 Pharmacokinetics #3
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  • Nursing, Pharmacology, Wolters Kluwer Health, noncompetitive antagonists,  Onset,  Agonists

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