Karch Chapter_25.ppt - Chapter 25 Muscle Relaxants...

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins Chapter 25: Muscle Relaxants Chapter 25: Muscle Relaxants
Copyright © 2017 Wolters Kluwer • All Rights Reserved Regulation of Movement and Control of Muscles Regulation of Movement and Control of Muscles Many injuries and accidents result in local damage to muscles or the skeletal anchors of muscles. These injuries may lead to muscle spasm and pain Reflex Arc Showing Pathway of Impulses Reflex Arc Showing Pathway of Impulses
Copyright © 2017 Wolters Kluwer • All Rights Reserved Neuromuscular Abnormalities Neuromuscular Abnormalities Muscle Spasm Often results from injury to the musculoskeletal system Caused by the flood of sensory impulses coming to the spinal cord from the injured area Muscle Spasticity Result of damage to neurons within the CNS May result from an increase in excitatory influences or a decrease in inhibitory influences within the CNS
Copyright © 2017 Wolters Kluwer • All Rights Reserved Action of Skeletal Muscle Relaxants Action of Skeletal Muscle Relaxants Most Relaxants Work in the brain and spinal cord Interfere with cycle of muscle spasm and pain Botulinum Toxins and Dantrolene Enter muscle fibers directly
Copyright © 2017 Wolters Kluwer • All Rights Reserved Action of Centrally Acting Skeletal Muscle Relaxants Action of Centrally Acting Skeletal Muscle Relaxants

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