Sources of Cells • where do we get the cell? There are different cell sources available. They are: • Autologous: Cell can be taken from the donor and introduced back to donor itself i.e., where donor and recipient are same. Limited supply and the donor site surgery are the major drawbacks. • Allogenic: Cells can be transferred from donor to recipient of same species. However, difficult to reduce the patients risk against the transplant antigens. • Syngeneic: Cells can be transplanted between genetically identical twins. Using this method, only twins can benefit but not other living beings. • Xenogenic: Cells transplantation is between species. Where transmission of new diseases; and immune rejection concern. Cells from different sources
Stem cells A life story…
What is a stem cell? stem cell stem cell SELF-RENEWAL (copying) specialized cell e.g. muscle cell, nerve cell DIFFERENTIATION (specializing)
What is a stem cell? Identical stem cells Stem cell SELF-RENEWAL (copying) Stem cell Specialized cells DIFFERENTIATION (specializing)
Why self-renew AND differentiate?
You've reached the end of your free preview.
Want to read all 23 pages?
- Fall '19
- Sources of Cells