Synthesis of p-Nitroacetanilide.docx

Synthesis of p-Nitroacetanilide.docx - Professor Dr Ryan...

This preview shows page 1 out of 1 page.

Professor Dr. Ryan Cassell Bruno Quiroga CHM2211L - TH 1:00-4:20pm March 11 th , 2018 Experiment 4 – Synthesis of p-Nitroacetanilide Purpose The aim of this experiment was to nitrate Acetanilide in order to synthesize p- Nitroacetanilide. It was also aimed at understanding how different substituents in a benzene ring can affect the outcome of an electrophilic substitution. Introduction Aromatic compounds are highly stable molecules and, unlike alkenes, they are unreactive to nucleophilic substitutions and additions. However, due to the nucleophilic nature of aromatic substances, they do participate in electrophilic substitutions. For these reactions to occur, the production of an electrophile is essential, which is usually catalyzed by the presence of a Lewis acid. In a nitration reaction, sulfuric acid (stronger acid) and nitric acid (weaker acid) are used to produce the Nitronium ion which would then be used as an electrophile.
Image of page 1
  • Summer '15
  • Atom, Electron, Electric charge, Electrophilic aromatic substitution

{[ snackBarMessage ]}

What students are saying

  • Left Quote Icon

    As a current student on this bumpy collegiate pathway, I stumbled upon Course Hero, where I can find study resources for nearly all my courses, get online help from tutors 24/7, and even share my old projects, papers, and lecture notes with other students.

    Student Picture

    Kiran Temple University Fox School of Business ‘17, Course Hero Intern

  • Left Quote Icon

    I cannot even describe how much Course Hero helped me this summer. It’s truly become something I can always rely on and help me. In the end, I was not only able to survive summer classes, but I was able to thrive thanks to Course Hero.

    Student Picture

    Dana University of Pennsylvania ‘17, Course Hero Intern

  • Left Quote Icon

    The ability to access any university’s resources through Course Hero proved invaluable in my case. I was behind on Tulane coursework and actually used UCLA’s materials to help me move forward and get everything together on time.

    Student Picture

    Jill Tulane University ‘16, Course Hero Intern