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Unformatted text preview: BICD100 Genetics Study Guide for Final Exam The ﬁnal exam will consist of 8 problems on the following topics: 1. A Mendelian dihybrid cross involving genetic interactions 2. Three factor mapping in Drosophila (or other diploid) e.g. Midterm 2 Q2 3. Human pedigree analysis Modes of inheritance Conditional probability (but not Bayes theorem!) 4. A three-gene yeast tetrad analysis problem Linked versus unlinked genes. Centromere mapping. e.g. Midterm 2 Q3 5. Bacterial mapping using time-of-entry in conjugation and ﬁne mapping using recombination e.g. Midterm 2 Q5 6. Mapping and complementation testing in bacteriophage e.g. PS 3A 7. Hardy-Weinberg equilibrium Observed and expected genotype frequencies Chi-squared goodness of ﬁt test 8. Chromosome aberrations and polyploidy. Behavior of translocation heterozygotes in meiosis Disjunction of autotetraploids e.g. PS 3B The level of difﬁculty will resemble that of the midterms and will not be as extreme as the problem sets. You will have 3 hours for the exam although I will aim for one that is doable in 2. All relevant equations and tables will be provided. You will need a calculator. ...
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This note was uploaded on 05/31/2009 for the course BICD 100 taught by Professor Nehring during the Spring '08 term at UCSD.
- Spring '08