10 endocrinol

10 endocrinol - Introduction to Endocrinology Birth of a...

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Introduction to Endocrinology Birth of a discipline: endocrinology What are hormones? Levels of analysis of hormone action Where do they come from? What do they do? How do they function?
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Effects of Castration Domestic animals  – lack of secondary sexual characteristics, more docile, meat  more tender, increase weight …  – short in stature, prostate impalpable feminine voice 
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Berthold (1849)
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Principle of Hormone Action Be rtho ld (1849):  m e c ha nis m  o f e ffe c t =>  c he m ic a l  no t ne rvo us Be rna rd (1855):  o b s e rva tio n tha t live r s e c re te s  s ug a r into  b lo o d => s pe c ia l o rg a ns  (g la nds ) tha t po ur the ir  c he m ic a l  s e c re tio ns   dire c tly into  b lo o ds tre a m   => hormones  coordinate functions  of different body tissues conceived of complex system of chemical messengers
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Testosterone & Secondary Characteristics 18-day old chick Selye + T injection
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This note was uploaded on 05/31/2009 for the course BAA 171 taught by Professor Drea during the Fall '07 term at Duke.

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10 endocrinol - Introduction to Endocrinology Birth of a...

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