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16_Horm___F_behav2

16_Horm___F_behav2 - Hormonal Cycle of Female Rhesus...

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Hormonal Cycle of Female Rhesus Follicular Periovulatory (E2 surge) Luteal (P surge) NOTE: covariation of T and E2
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Role of Adrenal Androgens in Female Sexual Behavior? Results: most women lost their sexual desire postoperative decrease in intercourse Subjects:   29 women (mean age = 51 yrs) Interpretation: adrenal critical to maintenance of libido Problem: no critical control condition  (i.e., adrenalectomy without ovariectomy) Procedures:   simultaneous ovariectomy & adrenalectomy  (for Rx of metatastic breast cancer) Waxenberg, Drellich, & Sutherland (1959)
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Adrenal Androgen Suppression Dexamethasone (DEX)   synthetic adrenocortical steroid suppresses inflammation & immune response chronic Rx suppresses adrenal function => suppresses androgen production
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Adrenal Suppression Study: Procedures Procedure: studied FF for 2 menstrual cycles during breeding season during 1 cycle: Dex administered via SC osmotic minipump
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