21 CAH & AI part 1

21 CAH & AI part 1 - Genetic Sex Gonadal Sex Body...

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XX => no HY antigen Ovary  => no MIS, no T uterus, cervix, fallopian tube, upper vagina clitoris labia minora & urethra labia majora indiff gonad Mullerian Wolffian genital tubercle groove swellings Genetic Sex Gonadal Sex Body Sex (internal) Body Sex (external) XY => HY antigen Testis  => MIS, T vas deferens, prostate seminal vesicle penis penile urethra scrotum indiff gonad Mullerian Wolffian genital tubercle groove swellings regress regress still no T T & DHT
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Sequential Events in Sexual Differentiation genetic sex gonadal sex   body sex   (internal  brain sex (behavior)
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Neurogenesis Only 50% migrate successfully  ( the others perish ).  Neural stem cells : source of new brain cells  divide in 2 main areas (inset):  ventricles hippocampus As stem cells proliferate, give rise to:  other neural stem cells neural precursors into either:  neurons  or  support cells   (glial cells).  
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21 CAH & AI part 1 - Genetic Sex Gonadal Sex Body...

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