22 Sex diff brain part 1

22 Sex diff brain part 1 - Endocrine Disrupters DES...

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Unformatted text preview: Endocrine Disrupters DES & synthetic progestins : given to women to prevent abortions; have androgenic properties. Genetic F from DES pregnancies much like CAH F (without salt wasting). Agricultural chemicals & pesticides : have estrogenic properties; associated w/ increased risk of urogenital malformations The increased risk of cryptorchidism among sons of F gardeners suggests association with prenatal exposure to chemicals. Summary of Revealing Cases * 5-alpha reductase deficiency in genetic male (penis at 12 syndrome) * CAH in genetic female => phenotypic male * AI in genetic male => phenotypic female * DES (diethylstilbestrol) women (like CAH) * Endocrine disrupters in men Points to Ponder * A woman with CAH was banned from competing in the Olympic Games as a woman. Do you agree with this decision? * Do you think a person with male (XY) chromosomes but suffering from AI should be allowed...
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22 Sex diff brain part 1 - Endocrine Disrupters DES...

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