exercise_3 - External Concentration (mM) Na + 3.6 109 K +...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Cellular and Molecular Neuroscience 2004 Exercise # 3 1) Imagine that you are doing some experiments, but imagine a manipulation where you change the ionic concentration of sodium in the extracellular bath. Let’s say now that the ionic concentrations in and out of the cell are: Ion Internal Concentration (mM) External Concentration (mM) Na + 3.6 55 K + 124 2.3 Draw the waveform of the action potential, particularly detailing the resting potential and the amount of overshoot. Below, on the same time scale, draw reasonable curves that describe the sodium conductance and the potassium conductance as a function of time. 2) Do the same as above but imagine now that the ionic concentrations are the following: Ion Internal Concentration (mM)
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Background image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: External Concentration (mM) Na + 3.6 109 K + 124 23.0 Make some kind of smirking comment about the resting potential in this case. 3) Assume the thing below is a piece of axon. First of all, it is not to scale. I think you can get past that. Assume a reasonable constant of proportionality between axon diameter and the space constant (maybe something like 3000 or there abouts). Draw the voltage waveform that appears as a function of length as an action potential travels down the axon. What about if something horrible happens and this axon gets demyelinated such that the conductance across the membrane gets quadrupled? 100 nm soma 0 mm 2 mm 4 mm-2 mm...
View Full Document

Page1 / 2

exercise_3 - External Concentration (mM) Na + 3.6 109 K +...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online