Running head: ASTHMA 1 Asthma Lori Morgan Walden University Advanced Pharmacology NURS-6521N Dr. Banks June 23, 2019
ASTHMA 2 Asthma Asthma is a common disease that affects many people around the world. There are approximately 25.7 million people in the United States are diagnosed with this respiratory disorder (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). It is a heterogeneous inflammatory condition that is chronic (Arcangelo et al., 2017). The advanced practice nurse (APN) must understand the best treatment options, especially for those suffering an acute asthma attack. The purpose of this discussion is to describe long-term control and quick-relief treatment options for these patients and the impact the drugs might have. Additionally, explain the stepwise approach to asthma treatment and management. Lastly, discuss how stepwise management assists health care providers and patients in gaining and maintaining control of the disease. Asthma Asthma is identified as airway narrowing and hyperresponsiveness (Arcangelo et al., 2017). There are many physical compositions that make up asthma, such as allergic, nonallergic, late-onset, fixed airflow limitation, and obesity (Arcangelo et al., 2017). The many triggers that result in symptoms are exercise, weather changes, inhaling irritants, upper respiratory infections, and allergens (Arcangelo et al., 2017). Through spasm, inflammation, and hypersecretion associated with the airway hyperresponsiveness it results in reversible airway obstruction by the infiltration of eosinophils and CD4 T helper cells (Villasenor et al., 2017). Treatment of the symptoms are crucial to the patient’s outcome. Medication Options Chronic maintenance therapy, support, and a care plan are essential in the effective treatment of the patient. All persons with asthma must use a short-acting bronchodilator, which is considered an asthma controller medication in those with persistent asthma (Arcangelo et al.,
ASTHMA 3 2017). The main drugs used to manage, and control asthma is leukotriene receptor antagonists, inhaled corticosteroids (ICS), and long-acting B 2 -agonist (Arcangelo et al., 2017). According to Barnes (2010), ICS used in combination with a B 2 -agonists can further improve asthma control. The many drugs that are used to treat asthma are administered different ways. The classes of drugs used are B 2 -adrenergic agonists, corticosteroids, leukotriene modifiers, mast cell stabilizers, methylxanthines, and an anti-inflammatory Omalizumab (Arcangelo et al., 2017).
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