Hypertension in the elderly.pdf

Hypertension in the elderly.pdf - Hypertension in the...

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10/11/2018 Hypertension in the elderly 1/22 Go to: Go to: World J Cardiol . 2012 May 26; 4(5): 135–147. Published online 2012 May 26. doi: 10.4330/wjc.v4.i5.135 PMCID: PMC3364500 PMID: 22655162 Hypertension in the elderly Nikolaos Lionakis , Dimitrios Mendrinos , Elias Sanidas , Georgios Favatas , and Maria Georgopoulou Nikolaos Lionakis, Dimitrios Mendrinos, Georgios Favatas, Maria Georgopoulou, Department of Cardiology, General Hospital of Nafplio, Asklipiou and Kolokotroni St, 21100 Nafplio, Greece Elias Sanidas, Columbia University, Medical Center and the Cardiovascular Research Foundation, 557 West 148th St, New York, NY 10031, United States Author contributions: Lionakis N and Mendrinos D wrote the manuscript; Lionakis N, Sanidas E, Favatas G and Georgopoulou M reviewed the manuscript and made the final corrections before submission; all authors have read and approved the final version. Correspondence to: Dr. Nikolaos Lionakis, Department of Cardiology, General Hospital of Nafplio, Asklipiou and Kolokotroni St, 21100 Nafplio, Greece. [email protected] Telephone: +30­2752­361155 Fax: +30­2752­361122 Received 2012 Mar 22; Revised 2012 Apr 25; Accepted 2012 May 2. Copyright ©2012 Baishideng Publishing Group Co., Limited. All rights reserved. This article has been cited by other articles in PMC. Abstract The elderly are the most rapidly growing population group in the world. Data collected over a 30­year period have demonstrated the increasing prevalence of hypertension with age. The risk of coronary artery disease, stroke, congestive heart disease, chronic kidney insufficiency and dementia is also increased in this subgroup of hypertensives. Hypertension in the elderly patients represents a management dilemma to cardiovascular specialists and other practioners. During the last years and before the findings of the Systolic Hypertension in Europe Trial were published, the general medical opinion considered not to decrease blood pressure values similarly to other younger patients, in order to avoid possible ischemic events and poor oxygenation of the organs (brain, heart, kidney). The aim of this review article is to highlight the importance of treating hypertension in aged population in order to improve their quality of life and lower the incidence of the cardiovascular complications. Keywords: Hypertension, Elderly, Pathophysiology, Treatment INTRODUCTION Aging is an inevitable part of life and brings along two inconvenient events: physiologic decline and disease state[ 1 ]. Hypertension is an important risk factor for cardiovascular morbidity and mortality, particularly in the elderly. It is a significant and often asymptomatic chronic disease, which requires optimal control and persistent adherence to prescribed medication to reduce the risks of cardiovascular, cerebrovascular and renal disease[ 2 ]. Hypertension in the elderly patients represents a management dilemma to cardiovascular (CV) specialists and other practioners. Furthermore, with the wide adoption
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