CellcycleLecture1 - The typical human produces how many new...

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The typical human produces how many new cells every minute? A.10 2 (100) B.10 5 (100,000) C.10 7 (10,000,000) D.10 9 (1,000,000,000) E.10 11 (100,000,000,000)
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The cell cycle is all about ______. A. Mitosis B. Meiosis C. Microtubules D. Cell division E. Genetic fidelity
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What is essential in cell division?
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Each stage is characterized by a distinct pattern of cellular synthesis. G1 - Gap between mitosis and start of DNA synthesis. P rotein and RNA synthesis. Carbohydrates and lipids being produced - strong cell growth. S - Synthesis - DNA synthesis. Phase that is responsible for duplicating DNA in the cell. Uniquely marked by DNA replication. G2 - GAP between S and Mitosis. Synthesis of proteins necessary for the mechanics of mitosis. G2 is often very brief.
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Time for cell cycle differs between different cell types. Very short - cell cycle times of 1 hour Very long - greater than 1 year. Variation is almost all found in the length of G1. embryonic cells - virtually no G1. Quiescent cells - G1 that essentially lasts forever (G0).
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What is needed in a basic cell cycle control system. 1. Be able to turn on each event at a specific time. 2. Have to initiate events in the correct order; i.e. entry into mitosis must always come after DNA replication. 3. Each event has to happen only once per cycle.
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What is needed in a basic cell cycle control system. 4. Need an on/off switch. Can’t begin a process, but not finish, don’t want to initiate chromosome condensation, and not finish. 5. Robust system, don’t want something that’s finicky and always breaking down. 6. Adaptable system, want to be able to modify, respond to a change in conditions.
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G1 Exit M Enter M Enter S Trigger anaphase and proceed to cytokinesis Replicate DNA Trigger DNA replication machinery Trigger mitosis machinery Assemble Mitotic Spindle G2 Checkpoint G1 Checkpoint Metaphase Checkpoint Is all DNA replicated?
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This note was uploaded on 03/31/2008 for the course MMG 409 taught by Professor Arvidson during the Spring '08 term at Michigan State University.

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CellcycleLecture1 - The typical human produces how many new...

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