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# handout10 - Lecture 10 Gene and Genotypic Frequencies At...

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1 Lecture 10 Gene and Genotypic Frequencies At Equilibrium Within a generation there is a relationship between gene and genotypic frequencies such that if the f(A) is p then f(AA) is p 2 . Across generations, gene and genotypic frequencies remain constant. At Equilibrium (Autosomal Locus) f(A) = p f(a) = q AA = p 2 Aa = 2pq aa = q 2

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2 Gene and Genotypic Frequency (Sex Linked) Sex Linked Frequency Genotype Population Within sex In the population, 1/2 of the individuals are male and 1/2 are females; therefore, frequencies are halved. The frequency within sex are conditional; for example, the frequency of X A Y given male is P(X A Y/male) = P(X A Y) = p/2 = p P(male) 1/2 Sex Linked Frequency Genotype Population Within sex males X A Y p/2 p X a Y q/2 q