handout10 - Lecture 10 Gene and Genotypic Frequencies At...

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1 Lecture 10 Gene and Genotypic Frequencies At Equilibrium Within a generation there is a relationship between gene and genotypic frequencies such that if the f(A) is p then f(AA) is p 2 . Across generations, gene and genotypic frequencies remain constant. At Equilibrium (Autosomal Locus) f(A) = p f(a) = q AA = p 2 Aa = 2pq aa = q 2
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2 Gene and Genotypic Frequency (Sex Linked) Sex Linked Frequency Genotype Population Within sex In the population, 1/2 of the individuals are male and 1/2 are females; therefore, frequencies are halved. The frequency within sex are conditional; for example, the frequency of X A Y given male is P(X A Y/male) = P(X A Y)= p/2 = p P(male) 1/2 Sex Linked Frequency Genotype Population Within sex males X A Y p/2 p X a Y q/2 q
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Sex Linked Frequency Genotype Population Within sex At equilibrium, gene frequencies can easily be obtained as the phenotypic (hence, genotypic) frequency among males. Sex Linked Frequency Genotype Population Within sex males X A Y p/2 p X a Y q/2 q females X A X A p 2 /2 p 2 X A X a 2pq/2 2pq X a X a q 2 /2 q 2
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handout10 - Lecture 10 Gene and Genotypic Frequencies At...

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