handout9 - Lecture 9 Population Genetics Population...

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1 Lecture 9 Population Genetics Population Genetics The study of populations over time with particular attention paid to gene and genotypic frequencies. “The individual is mortal. Date of birth and death can be documented. The population, practically speaking, is immortal.” (JAY L. LUSH) Gene and Genotypic Frequencies Codominant (M = N) Genotype Phenotype # observed MM M 130,000 MN MN 265,000 NNN 105,000 500,000 people 1,000,000 genes
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2 Genotypic frequencies f(MM) = #MM = 130,000 = .26 TOTAL 500,000 f(MN) = = .53 f(NN) = = .21 1.00 With codominance it is easy to calculate frequencies. f(M gene) = # of M = 2(#MM) + (#MN) total genes 2 (# of people) f(N gene) = 1 - f(M) Gene frequencies Gene frequencies Note: Computing gene frequencies from genotypic frequencies f(M gene) = 2(#MM) + (#MN) 2 (# of people) = 2(#MM) + (#MN) 2 (# of people) 2 (# of people) = f(MM) + 1/2 f(MN)
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3 Gene frequencies f(M) = f(MM) + 1/2 f(MN) = .26 +1/2 (.53) = .525 f(N) = f(NN) +
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handout9 - Lecture 9 Population Genetics Population...

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