handout13-1 - Lecture 13 Selection Selection Against a...

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1 Lecture 13 Selection Selection Against a Recessive Gene -- The problem is the recessive alleles is hidden in the heterozygotes. In natural populations there is nothing more. With artificial selection can target heterozygotes. -- Purging complete families is often impractical. Also for many species males are more important reproductively than females. Design a progeny test for screening potential parents. Progeny test -- create progeny to learn about parent genotypes
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2 Consider the following example: Mating between Bb and bb 1/2Bb +1/2bb Possible Outcomes Progeny Genotypes Bb bb P(outcome) 3 0 .125 .125 2 1 .375 1 2 .375 0 3 .125 P(all Bb) Consider the following example: Possible Outcomes Progeny Genotypes Bb bb P(outcome) 3 0 .125 .125 2 1 .375 1 2 .375 .875 0 3 .125 P(at least one bb) or probability of seeing the b allele from Bb parent. Progeny Test Program. Bb × Bb 3 B_ + 1 bb 1/3 BB + 2/3 Bb Progeny Test: B_ × bb n = 3 progeny observed
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3 If _ is b what is the probability we will detect it? P(at least one bb progeny) = P(detection)
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handout13-1 - Lecture 13 Selection Selection Against a...

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