Week 6 Discussion.docx - Week 6 Discussion Tanisha Flowers Walden University Advanced Pharmacology Dr Funda Tiryaki April 6 2016 Osetoarthritis(OA is a

Week 6 Discussion.docx - Week 6 Discussion Tanisha Flowers...

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Week 6 Discussion Tanisha Flowers Walden University Advanced Pharmacology Dr. Funda Tiryaki April 6, 2016 Osetoarthritis (OA) is a common, progressive disease that can result in chronic pain affecting the joints. There are two forms. Primary or idiopathic resulting from physiologic changes that occur with normal aging and secondary OA resulting from traumatic injuries or inherited conditions (Arcangelo & Peterson, 2013). Cartilage undergoes a remodeling process, stimulated by joint movement or use. In OA, this process is altered by a combination of mechanical, cellular, biochemical processes, resulting in abnormal reparation of cartilage and an increase in cartilage degradation (Dewing, Setter, & Slusher, 2012). OA is characterized by local areas of loss and damage of articular cartilage, new bone formation of joint margins, subchondral bone changes variable degrees of mid synovitis, and thickening of the joint capsule (Huether & McCance, 2012).
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  • Summer '15
  • Paracetamol, Non-steroidal anti-inflammatory drug, Arcangelo & Peterson

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