Unformatted text preview: • Enzymes are biological catalysts with high specificity • Origins • Ribozymes (RNA) • Proteins • Terms • Substrate -- Product (but, keep in mind equilibrium constant) • Active site • Enzyme-Substrate complex • E + S -> ES -> E + P • Free energy graph • Important enzyme facts: do not change equilibrium, do not change DG, change Energy of ac-tivation, speed reactions, equilibrium and reverse reaction still apply! • Substrate concentration affects reaction rate: graph rate by conc • Regulation of enzyme action • Allosteric enzyme respond to stimulus other than substrate by changing shape • Inactive + activator --> Active • Active + inhibitor --> Inactive • Example: Thr -> alphaKbut -> -> -> -> Ile • Ile inhibits first step...
View Full Document
This note was uploaded on 06/07/2009 for the course BIS BIS2A taught by Professor Lucacomai during the Spring '09 term at UC Davis.
- Spring '09