1_15_09_HodgkinHuxley

1_15_09_HodgkinHuxley - This circuits function depend on...

Info iconThis preview shows pages 1–10. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: This circuits function depend on nonlinear synaptic mechanisms. Today, we will focus on models for action potentials. Equivalent-circuit models for action potentials are RC circuits with many conductances. c m dV dt = ! i m + I e A If A is the membrane surface area, c m is the capacitance per unit area, and i m is the sum of all membrane currents per unit area, then i m = g L V ! E L ( ) + g K n 4 V ! E K ( ) + g Na m 3 h V ! E Na ( ) Disregarding synapses (g s ), and making n , m , and h the probabilities of opening of activation and inactivation of voltage-dependent gates, the Hodgkin-Huxley model is One can conceptualize these gates in molecular terms. A. K + channel B. Na + channel Individual channels are all-or-none and have random opening times. c m dV dt = ! i m + I e A If A is the membrane surface area, c m is the capacitance per unit area, and i m is the sum of all membrane currents per unit area, then i m = g L V ! E L ( ) + g K n 4 V ! E K ( ) + g Na m 3 h V ! E Na ( ) Disregarding synapses (g...
View Full Document

Page1 / 18

1_15_09_HodgkinHuxley - This circuits function depend on...

This preview shows document pages 1 - 10. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online