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1_15_09_HodgkinHuxley

1_15_09_HodgkinHuxley - Outline of the Lecture...

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Outline of the Lecture Outline of the Lecture Hodgkin-Huxley Model Hodgkin-Huxley Model Membrane Currents                 Channels            Gating  Membrane Currents                 Channels            Gating  Mechanisms Mechanisms      
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Voltage-dependent    Gating  Voltage-dependent    Gating  Mechanisms  Mediate  Mechanisms  Mediate  Action Potentials   Action Potentials      
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This circuit’s function depend on nonlinear synaptic mechanisms.
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Today, we will focus on models for action potentials.
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Equivalent-circuit models for action potentials are RC circuits with many conductances.
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c m dV dt = - ι μ + Ι ε Α If A is the membrane surface area, c m is the capacitance per unit area, and i m is the sum of all membrane currents per unit area, then i m = γ Λ ς - Ε Λ ( 29 + γ Κ ν 4 ς - Ε Κ ( 29 + γ Να μ 3 η ς - Ε Να ( 29 Disregarding synapses (g s ), and making n , m , and h
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